Screening Instrumentation
Microscopes
Capabilities: Fast, sensitive and flexible automated cell imaging using 4x, 10x, 20x (water immersion) or 40x (water immersion) objectives and filters for imaging DAPI, CFP, FITC, YFP, TRITC, Cy5, Cy7 and TexasRed. 60 µm pinhole confocality available and image analysis software, MetaXpress and IN Carta.
Applications: Broad range of high-content assays in 2D and 3D
Objectives:
|
Objective |
Image Resolution |
|
4x Air |
1.699 µm / px |
|
10x Air |
679 nm / px |
|
20x Water |
338.7 nm / px |
|
40x Water |
169.4 nm / px |
Filters equipped:
Capabilities: Long term real-time, non-invasive, quantitative live-cell analysis; 4x, 10x, and 20x objectives, HD phase-contrast, widefield fluorescence
Applications: Live-cell monitoring of e.g. proliferation, cell death, wound-healing, scratch assays.
Objectives:
|
Objective |
Image Resolution |
|
4x Air |
2.82 µm / px |
|
10x Air |
1.24 µm / px |
|
20x Air |
0.62 µm / px |
Filters equipped:
|
Filter set |
Excitation |
Emission |
|
Green |
441-481 nm |
503-544 nm |
|
Red |
567-607 nm |
622-704 nm |
Visit IncuCyte S3 Live-Cell Analysis System's website by clicking here.
Plate readers
Capabilities: A combined plate cytometer and plate reader with absorbance, fluorescence and luminescence capabilities, combined with brightfield and fluorescence well-imaging with single cell resolution.
Applications: Broad range of absorbance or luminescent based biological readouts; Nucleic Acid measurement
Objectives:
|
Objective |
Resolution |
|
4x Air |
3.0 µm |
Filters equipped (for microscopy):
|
Filter set |
Excitation |
|
Blue |
385 nm LED |
|
Green |
465 nm LED |
|
Orange |
525 nm LED |
|
Red |
632 nm LED |
|
Gray |
735 nm LED or Transmitted Light |
Visit EnSight Mulitimode plate reader's website by clicking here.
Automated Pipetting Platforms
Capabilities: Liquid transfer using disposable pipet tips (Hamilton); 384-well head; plate handling
Applications: automated cell splitting on multi-well plates, 2D and 3D culture fixation and staining, high-throughput screening
Capabilities: Liquid transfer using non-contact acoustic droplet ejection (tips-free); flexible low-volume transfer for high throughput formats.
Echo 550 for all liquid classes in 2.5nL drops.
Echo 525 for non-DMSO liquids in 25nL drops.
Applications: compound screens, dose-response curves, antibody staining, miniaturized combinatorial reagent addition, library cherry-pick, low-volume qPCR.
Capabilities: Peristaltic liquid dispensing using random access dispense (RAD) and multi-mode dispensing in 96 and 384-well microplates (1-3000 µL).
Applications: cell seeding, reagent dispensing
Capabilities: Microplate washing.
Applications: Washing of fixed as well as live cells.
Flow Cytometry
Capabilities:
- High throughput Flow cytometer designed to run standard 96 or 384-well plates.
- Offering Violet (6 filters), Blue (5 filters) and Red (2 filters) laser lines
- ZERO dead volume – your complete sample will be measured without worrying about dead volume losses
- Sample volumes down to 1 µl
Applications:
- Immunology, oncology, drug discovery, vaccine development
- Screening assays, biomarker discovery, characterizing complex cellular populations
Visit iQue Advanced Flow Cytometry´s website by clicking here.